HitPredict

Interactor 1: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Interactor 2: LIRB1 (Q8NHL6)
Leukocyte immunoglobulin-like receptor subfamily B member 1 (LIR-1) (Leukocyte immunoglobulin-like receptor 1) (CD85 antigen-like family member J) (Immunoglobulin-like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD antigen CD85j)
Gene: LILRB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	16455647, 24018270, 27649529, 12853576
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~Ig_2
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0042803 - protein homodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Hs			1 650
+	Hs
		382485 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		LIRB1_HUMAN (1-650): 2.42e-147: 443: 100.00
+	Hs
		382478 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		LIRB2_HUMAN (1-650): 2.34e-117: 364: 76.31
+	Hs
		382420 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		KI3S1_HUMAN (1-334): 4.36e-69: 231: 35.91
+	Hs
		382341 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		KI3L2_HUMAN (1-334): 1.36e-63: 219: 35.91
+	Hs
		798244 Q5S3G3_HUMAN (2-116): 3.35e-46: 154: 22.41		KI3L2_HUMAN (1-334): 1.36e-63: 219: 35.91
+	Hs
		798280 Q5S3G3_HUMAN (2-116): 3.35e-46: 154: 22.41		KI2S4_HUMAN (120-337): 1.27e-52: 185: 38.36
+	Hs
		798193 Q5QT33_HUMAN (2-117): 3.07e-47: 157: 21.37		KI2L3_HUMAN (319-581): 5.31e-33: 131: 22.92
+	Hs
		798194 Q5RIP0_HUMAN (2-117): 8.15e-47: 155: 20.51		KI2L3_HUMAN (319-581): 5.31e-33: 131: 22.92
+	Hs
		87224 C9E8W1_HUMAN (2-117): 1.13e-46: 155: 20.51		KI2L3_HUMAN (319-581): 5.31e-33: 131: 22.92
+	Hs
		798195 Q5S3G3_HUMAN (2-116): 3.35e-46: 154: 22.41		KI2L3_HUMAN (319-581): 5.31e-33: 131: 22.92
+	Hs
		798172 Q5QT33_HUMAN (2-117): 3.07e-47: 157: 21.37		KI2L2_HUMAN (319-581): 4.84e-31: 126: 22.33
+	Hs
		86373 C1K0Y5_HUMAN (2-117): 2.88e-47: 157: 21.37		KI2L2_HUMAN (319-581): 4.84e-31: 126: 22.33
+	Hs
		798173 Q5RIP0_HUMAN (2-117): 8.15e-47: 155: 20.51		KI2L2_HUMAN (319-581): 4.84e-31: 126: 22.33
+	Hs
		87223 C9E8W1_HUMAN (2-117): 1.13e-46: 155: 20.51		KI2L2_HUMAN (319-581): 4.84e-31: 126: 22.33
+	Hs
		382484 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		LIRB4_HUMAN (119-586): 1.76e-29: 124: 19.83
+	Hs
		798147 Q5QT33_HUMAN (2-117): 3.07e-47: 157: 21.37		KI2L1_HUMAN (319-581): 8.17e-30: 122: 20.33
+	Hs
		86372 C1K0Y5_HUMAN (2-117): 2.88e-47: 157: 21.37		KI2L1_HUMAN (319-581): 8.17e-30: 122: 20.33
+	Hs
		798148 Q5RIP0_HUMAN (2-117): 8.15e-47: 155: 20.51		KI2L1_HUMAN (319-581): 8.17e-30: 122: 20.33
+	Hs
		87222 C9E8W1_HUMAN (2-117): 1.13e-46: 155: 20.51		KI2L1_HUMAN (319-581): 8.17e-30: 122: 20.33
+	Hs
		47499 HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41		A0A8I5QEB2_HUMAN (319-536): 2.04e-18: 90.1: 21.88