HitPredict

Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36089195, 29044188
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 136
+	Hs
		904578 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		904860 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		883487 MECP2_HUMAN (1-486): 5.18e-113: 344: 100.00		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		331659 MBD4_HUMAN (99-480): 9.43e-45: 167: 20.05		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		331661 MBD4_HUMAN (99-480): 9.43e-45: 167: 20.05		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		352107 MBD3_HUMAN (93-249): 3.07e-43: 156: 26.88		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		352108 MBD3_HUMAN (93-249): 3.07e-43: 156: 26.88		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		352152 MBD3_HUMAN (93-249): 3.07e-43: 156: 26.88		H31T_HUMAN (1-136): 2.59e-59: 181: 93.38
+	Hs
		998900 MBD2_HUMAN (75-249): 3.33e-38: 146: 28.65		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		998923 MBD1_HUMAN (95-220): 7.01e-31: 127: 31.78		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		883728 MBD1_HUMAN (95-220): 7.01e-31: 127: 31.78		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76
+	Hs
		998611 TITIN_HUMAN (240-472): 1.29e-12: 72.8: 19.57		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1258894 TITIN_HUMAN (240-472): 1.29e-12: 72.8: 19.57		H32_HUMAN (1-136): 5.34e-59: 180: 97.06
+	Hs
		998438 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		H31_HUMAN (1-136): 3.09e-60: 183: 96.32
+	Hs
		1016949 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		H33_HUMAN (1-136): 1.13e-59: 182: 100.00
+	Hs
		883582 NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06		CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76