HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PTN21 (Q16825)
Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1)
Gene: PTPN21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1174
+	Hs
		909614 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN21_HUMAN (1-1174): 0: 888: 100.00
+	Hs
		909595 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN14_HUMAN (3-1174): 0: 813: 52.54
+	Hs
		904597 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PTN14_HUMAN (3-1174): 0: 813: 52.54
+	Hs
		204644 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		E41L2_HUMAN (7-542): 3.43e-125: 411: 23.99
+	Hs
		910185 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		E41L3_HUMAN (15-899): 2.79e-124: 411: 16.94
+	Hs
		204643 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E41L2_HUMAN (7-542): 3.43e-125: 411: 23.99
+	Hs
		905282 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E41L3_HUMAN (15-899): 2.79e-124: 411: 16.94
+	Hs
		204653 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		E41L2_HUMAN (7-542): 3.43e-125: 411: 23.99
+	Hs
		905141 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E41L5_HUMAN (18-664): 1.05e-118: 386: 20.18
+	Hs
		505612 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		EPB41_HUMAN (2-564): 6.62e-114: 377: 21.58
+	Hs
		910025 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		E41L1_HUMAN (6-646): 4.59e-113: 375: 18.81
+	Hs
		505611 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		EPB41_HUMAN (2-564): 6.62e-114: 377: 21.58
+	Hs
		905110 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		E41L1_HUMAN (6-646): 4.59e-113: 375: 18.81
+	Hs
		904784 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		FRMD5_HUMAN (24-418): 1.44e-114: 370: 23.78
+	Hs
		663970 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN4_HUMAN (1-542): 1.91e-106: 358: 23.17
+	Hs
		663969 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PTN4_HUMAN (1-542): 1.91e-106: 358: 23.17
+	Hs
		640229 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN3_HUMAN (5-413): 4.67e-90: 312: 23.83
+	Hs
		640228 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PTN3_HUMAN (5-413): 4.67e-90: 312: 23.83
+	Hs
		909498 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN13_HUMAN (27-316): 2.37e-17: 90.5: 28.39
+	Hs
		904503 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PTN13_HUMAN (27-316): 2.37e-17: 90.5: 28.39