HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: TTBK1 (Q5TCY1)
Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase)
Gene: TTBK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1321
+	Hs
		910182 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST1_HUMAN (1-1290): 1.96e-168: 545: 15.38
+	Hs
		909684 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MAST2_HUMAN (1-1294): 2.99e-147: 491: 13.31
+	Hs
		909658 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MRCKA_HUMAN (2-1032): 1.18e-135: 458: 12.50
+	Hs
		909524 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ROCK1_HUMAN (14-861): 6.35e-125: 422: 13.15
+	Hs
		647862 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MARK3_HUMAN (7-752): 5.7e-130: 420: 14.29
+	Mm
		910231 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		MARK3_MOUSE (7-752): 4.49e-129: 417: 14.81
+	Hs
		909810 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MINK1_HUMAN (28-925): 2.88e-123: 416: 14.56
+	Xl
		223344 O57468_XENLA (1-244): 4.25e-141: 397: 63.12		Q804T2_XENLA (7-752): 4.88e-128: 414: 14.51
+	Mm
		905331 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		MARK3_MOUSE (7-752): 4.49e-129: 417: 14.81
+	Xl
		223345 O57468_XENLA (1-244): 4.25e-141: 397: 63.12		Q8QGV3_XENLA (2-752): 1.03e-122: 401: 14.50
+	At
		1280891 14337_ARATH (3-244): 3.18e-142: 400: 60.25		CIPKC_ARATH (20-382): 7.86e-123: 392: 16.89
+	At
		788672 14333_ARATH (1-244): 4.4e-142: 400: 61.79		CIPKC_ARATH (20-382): 7.86e-123: 392: 16.89
+	Hs
		909730 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MARK2_HUMAN (4-692): 6.32e-120: 394: 16.49
+	At
		965360 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CIPKC_ARATH (20-382): 7.86e-123: 392: 16.89
+	Mm
		910234 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		MARK2_MOUSE (4-692): 1.2e-115: 382: 15.10
+	Hs
		830323 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KC1E_HUMAN (26-440): 4.41e-120: 381: 29.31
+	Hs
		909507 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AAPK1_HUMAN (24-547): 3.57e-117: 379: 15.72
+	Rn
		871214 1433E_RAT (1-244): 2.02e-141: 398: 63.53		AAPK1_RAT (24-547): 9.26e-117: 378: 15.54
+	Hs
		822234 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KC1D_HUMAN (26-448): 8.34e-116: 370: 30.70
+	Hs
		821971 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KC1A_HUMAN (20-348): 1.94e-115: 366: 31.55