HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SH3B4 (Q9P0V3)
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)
Gene: SH3BP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	33761321, 33961781, 35271311, 36931259, 20936779, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid pooling approach, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 963
+	Hs
		910108 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		982565 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		910324 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		905357 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		935606 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		683771 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		927602 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		647337 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		1265696 1433B_MOUSE (2-247): 8.57e-109: 315: 75.81		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		926863 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		684365 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		933138 1433T_MOUSE (2-245): 3e-105: 306: 70.73		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		250874 1433S_MOUSE (2-236): 1.38e-95: 281: 65.96		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		909710 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MACC1_HUMAN (140-958): 0: 1340: 43.71