HitPredict

Interactor 1: 1433G (P61982)
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: Ywhag

Interactor 2: RAF1 (Q99N57)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20628654
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Mm			1 648
+	Hs
		373995 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		373992 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RAF1_HUMAN (1-648): 0: 717: 97.69
+	Hs
		110869 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		H7C560_HUMAN (40-647): 0: 597: 55.95
+	Hs
		542849 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		BRAF_HUMAN (40-647): 0: 596: 55.95
+	Mm
		655938 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		BRAF_MOUSE (2-647): 0: 591: 52.54
+	Hs
		542847 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		BRAF_HUMAN (40-647): 0: 596: 55.95
+	Gg
		982842 1433E_CHICK (1-244): 2.02e-141: 398: 63.53		BRAF_CHICK (39-647): 0: 589: 56.68
+	Mm
		655936 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		BRAF_MOUSE (2-647): 0: 591: 52.54
+	Gg
		982833 1433G_CHICK (1-247): 7.26e-140: 393: 99.60		BRAF_CHICK (39-647): 0: 589: 56.68
+	Hs
		46557 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		A0A2R8Y8E0_HUMAN (40-647): 0: 578: 52.87
+	Hs
		488645 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ARAF_HUMAN (46-646): 0: 556: 57.57
+	Hs
		488639 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ARAF_HUMAN (46-646): 0: 556: 57.57
+	Dm
		507708 1433E_DROME (1-243): 1.58e-140: 396: 63.37		KRAF1_DROME (40-647): 2.43e-156: 469: 46.42
+	At
		248524 14331_ARATH (4-244): 4.02e-141: 397: 59.67		SIRK_ARATH (11-609): 2.53e-150: 458: 16.49
+	At
		965320 14332_ARATH (4-244): 1.39e-141: 398: 61.32		BAK1_ARATH (171-647): 2.86e-142: 429: 16.32
+	At
		1277300 14337_ARATH (3-244): 3.18e-142: 400: 60.25		SERK1_ARATH (174-607): 1.09e-130: 400: 19.31
+	Mm
		910254 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		KSR1_MOUSE (138-648): 2.96e-119: 377: 26.38
+	Hs
		909779 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KSR1_HUMAN (138-648): 2.06e-113: 363: 24.70
+	At
		965327 14332_ARATH (4-244): 1.39e-141: 398: 61.32		PBS1_ARATH (273-641): 1.79e-111: 344: 21.74
+	Hs
		909702 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KSR2_HUMAN (332-623): 1.07e-43: 170: 35.08