HitPredict

Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 650 Hs			1 184
+	Mm
		988881 APLP2_MOUSE (42-648): 0: 843: 39.82		RAC1_MOUSE (1-184): 1.74e-77: 231: 27.55
+	Hs
		375440 APLP2_HUMAN (42-648): 0: 822: 35.25		RASK_HUMAN (1-167): 6.29e-55: 174: 57.49
+	Hs
		373896 APLP2_HUMAN (42-648): 0: 822: 35.25		RASN_HUMAN (1-167): 5.05e-54: 171: 56.89
+	Hs
		421886 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RAC1_HUMAN (1-184): 1.74e-77: 231: 27.55
+	Mm
		551405 A4_MOUSE (23-241): 1.65e-115: 364: 42.27		RB11A_MOUSE (4-178): 2.13e-69: 211: 28.98
+	Mm
		551482 A4_MOUSE (23-241): 1.65e-115: 364: 42.27		RAB14_MOUSE (4-178): 7.99e-69: 209: 33.52
+	Hs
		421840 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RAP1B_HUMAN (1-184): 1.97e-74: 223: 100.00
+	Hs
		423132 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RAB1B_HUMAN (4-179): 1.12e-71: 216: 29.94
+	Hs
		421868 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RB11A_HUMAN (4-178): 2.13e-69: 211: 28.98
+	Hs
		421835 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RAB14_HUMAN (4-178): 7.99e-69: 209: 33.52
+	Hs
		375083 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RASK_HUMAN (1-167): 6.29e-55: 174: 57.49
+	Hs
		422962 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RIT2_HUMAN (2-178): 1.4e-54: 174: 46.89
+	Hs
		373731 A4_HUMAN (41-243): 2.2e-109: 349: 42.16		RASN_HUMAN (1-167): 5.05e-54: 171: 56.89