HitPredict

Interactor 1: KS6A3 (P51812)
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
Gene: RPS6KA3

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 2554
+	Hs
		1148372 KS6A1_HUMAN (1-738): 0: 782: 78.11		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		1371559 KS6B2_HUMAN (420-727): 2.02e-117: 363: 29.76		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		1146445 KS6A2_HUMAN (7-332): 8.56e-100: 325: 23.67		USP9X_HUMAN (1-2554): 0: 3673: 100.00
+	Hs
		138909 AKT2_HUMAN (389-739): 5.94e-127: 388: 24.60		USP9Y_HUMAN (1-2554): 0: 3609: 91.59
+	Dm
		1463818 JIL1_DROME (25-728): 0: 565: 31.88		PUF_DROME (220-472): 3.53e-77: 289: 20.39
+	Hs
		1371755 KS6B2_HUMAN (420-727): 2.02e-117: 363: 29.76		UBP7_HUMAN (1469-2119): 6.29e-95: 336: 18.82
+	Hs
		605851 KAPCA_HUMAN (403-714): 2.31e-117: 358: 28.31		UBP22_HUMAN (1505-1919): 6.5e-99: 332: 18.14