HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 558
+	Hs
		910174 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Hs
		909532 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (1-556): 6.83e-143: 433: 24.32
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (2-556): 4.99e-141: 428: 24.16
+	At
		965291 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CDPK1_ARATH (6-341): 2.27e-138: 415: 32.84
+	At
		802001 14334_ARATH (4-255): 2.51e-145: 408: 73.62		CDPK1_ARATH (6-341): 2.27e-138: 415: 32.84
+	At
		788694 14335_ARATH (2-255): 3.04e-141: 398: 68.75		CDPK1_ARATH (6-341): 2.27e-138: 415: 32.84
+	Hs
		159186 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CSKP_HUMAN (10-308): 2.84e-83: 280: 46.08
+	Hs
		909811 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DCLK2_HUMAN (12-295): 9.49e-65: 227: 40.77
+	Mm
		910345 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DCLK1_MOUSE (11-272): 4.57e-65: 227: 44.15