HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: REEP1 (Q9H902)
Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein)
Gene: REEP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 17979178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0016020 - membrane GO:0031966 - mitochondrial membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 201
+	Hs
		909682 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		REEP3_HUMAN (1-191): 4.15e-81: 243: 66.49
+	Hs
		909967 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		REEP2_HUMAN (1-200): 5.29e-80: 240: 66.18
+	Hs
		910029 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		REEP4_HUMAN (1-182): 2.57e-76: 231: 66.48
+	At
		788367 14331_ARATH (4-245): 3.88e-144: 405: 75.41		HA22K_ARATH (1-171): 2.6e-58: 183: 26.01
+	Sc
		665118 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		YOP1_YEAST (6-99): 1.22e-34: 122: 27.66
+	Zm
		42212 B6SRI4_MAIZE (4-255): 1.29e-145: 409: 70.47		A0A1D6NY22_MAIZE (13-61): 1.61e-17: 75.2: 24.49