HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: GAB2 (Q9UQC2)
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)
Gene: GAB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	33961781, 35271311, 36931259, 19608861, 19172738
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 676
+	Mm
		910246 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		Q3ZB59_MOUSE (1-676): 0: 714: 91.31
+	Hs
		909527 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		GAB1_HUMAN (3-675): 0: 652: 37.36
+	Hs
		909638 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DOC11_HUMAN (2-457): 1.02e-111: 372: 16.08
+	Hs
		909680 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA7_HUMAN (6-456): 1.7e-80: 278: 14.62
+	Hs
		910041 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA2_HUMAN (2-229): 1.67e-55: 197: 21.55
+	Hs
		909993 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DOCK9_HUMAN (2-485): 1.15e-51: 196: 12.16
+	Hs
		910043 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA1_HUMAN (3-163): 2.62e-36: 142: 23.46
+	Hs
		910040 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHA5_HUMAN (6-453): 3.24e-26: 117: 15.35
+	Hs
		909748 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PHLB2_HUMAN (9-114): 2.45e-24: 111: 28.04
+	Hs
		909755 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PHLB1_HUMAN (8-113): 8.34e-17: 87: 26.27