HitPredict

Interactor 1: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Interactor 2: PEAK1 (Q9H792)
Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
Gene: PEAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Hs			1 1746
+	Hs
		962830 RND3_HUMAN (4-227): 5.97e-99: 289: 64.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		978309 RHOB_HUMAN (5-185): 8.64e-92: 269: 45.86		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		1015790 RHOG_HUMAN (7-193): 2.61e-84: 250: 41.71		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		962492 RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		1366885 RND1_HUMAN (6-227): 1.91e-83: 249: 53.15		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		466464 RHOC_HUMAN (9-193): 5.48e-82: 244: 48.11		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		581294 RAC2_HUMAN (8-195): 7.72e-79: 236: 40.43		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		953677 RAC3_HUMAN (8-182): 7.47e-79: 236: 42.86		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		988711 RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		976565 RB11A_HUMAN (3-224): 1.68e-76: 231: 21.08		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		126804 RHOD_HUMAN (9-191): 9.06e-55: 176: 43.48		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		605623 RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Hs
		466097 RHOC_HUMAN (9-193): 5.48e-82: 244: 48.11		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Hs
		728154 RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25		AKT1_HUMAN (1362-1695): 4.45e-91: 307: 15.07
+	Hs
		605631 RAC1_HUMAN (8-194): 9.85e-79: 236: 42.25		KAPCA_HUMAN (1345-1709): 1.11e-90: 301: 18.30
+	Hs
		962442 RHOA_HUMAN (9-193): 3.39e-84: 250: 47.03		PINK1_HUMAN (1357-1669): 2.88e-73: 258: 23.64
+	Hs
		1417051 RAB1B_HUMAN (2-224): 3.48e-77: 232: 19.64		PINK1_HUMAN (1357-1669): 2.88e-73: 258: 23.64
+	Ce
		145089 RHO1_CAEEL (9-184): 1.09e-82: 246: 50.00		UNC89_CAEEL (530-1704): 5.79e-21: 103: 12.80
+	Ce
		145082 RAC1_CAEEL (8-194): 1.65e-77: 233: 42.78		UNC89_CAEEL (530-1704): 5.79e-21: 103: 12.80
+	Ce
		110130 G5EBV3_CAEEL (1-194): 3.84e-76: 229: 37.11		UNC89_CAEEL (530-1704): 5.79e-21: 103: 12.80