HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras, Arm_3~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 191
+	Hs
		466164 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		RHOC_HUMAN (6-185): 8.96e-86: 252: 42.25
+	Hs
		911204 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93
+	Hs
		253606 IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		910840 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93
+	Hs
		142521 IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		911206 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		580943 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		RAC2_HUMAN (2-191): 3.12e-74: 223: 38.07
+	Hs
		911198 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61
+	Hs
		911200 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		RHOA_HUMAN (6-191): 3.36e-72: 218: 38.86
+	Hs
		910846 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		910832 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61