HitPredict

Interactor 1: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26186194, 26496610, 28514442, 24981860, 33961781, 35271311, 17643375, 15282305, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 172
+	Sp
		154257 RPB11_SCHPO (1-117): 1.69e-40: 132: 45.30		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		757321 RPB11_YEAST (1-110): 4.21e-45: 144: 50.00		RPB7_YEAST (1-171): 4.47e-63: 193: 42.78
+	Hs
		912263 RPB11_HUMAN (1-117): 1.88e-53: 164: 100.00		RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72
+	Hs
		516891 RPAC2_HUMAN (12-116): 3.58e-40: 131: 30.56		RPC8_HUMAN (1-172): 5.31e-54: 171: 18.72
+	Sc
		699993 RPAC2_YEAST (13-110): 5.05e-33: 114: 33.33		RPC8_YEAST (1-158): 1.08e-49: 160: 19.39