Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: IQEC1 (Q6DN90)
IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)
Gene: IQSEC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arf~IQ_SEC7_PH, Arf~Sec7
Common GO terms GO:0016020 - membrane
GO:0051549 - positive regulation of keratinocyte migration
GO:0120183 - positive regulation of focal adhesion disassembly
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 175
Hs

1 963
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024