HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1098
+	Hs
		925725 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		901043 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		545697 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		900762 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		915880 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		925239 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		900424 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		915639 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		545346 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		950954 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		900482 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SLMAP_HUMAN (659-1098): 1.13e-59: 222: 18.59
+	Mm
		925797 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		925799 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		1164086 RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		876347 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		925236 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		900421 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		915636 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		900710 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38
+	Hs
		915848 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		INADL_HUMAN (300-819): 1.83e-15: 84: 10.38