HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: MBD1 (Q9UIS9)
Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1)
Gene: MBD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 605
+	Hs
		917145 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2A_HUMAN (203-473): 4.74e-45: 174: 23.05
+	Hs
		641185 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DNMT1_HUMAN (249-383): 1.26e-41: 164: 24.44
+	Hs
		918135 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2B_HUMAN (220-385): 1.62e-39: 158: 23.53
+	Xl
		917053 H4_XENLA (1-103): 1.38e-48: 151: 100.00		P79922_XENLA (249-383): 3.51e-37: 150: 24.27
+	Hs
		918055 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CXXC1_HUMAN (241-404): 9.69e-36: 144: 29.38
+	Hs
		328519 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MBD3_HUMAN (7-69): 1.01e-29: 120: 50.79
+	Hs
		918072 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MBD2_HUMAN (6-69): 3.83e-26: 112: 57.81
+	Hs
		917624 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KDM2B_HUMAN (243-377): 3.11e-24: 110: 24.65
+	Hs
		918168 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KDM2A_HUMAN (243-379): 4.21e-19: 94.1: 23.03
+	Hs
		195827 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TET3_HUMAN (332-383): 1.66e-09: 63.3: 28.85