HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	27462807
Identification Methods	pull down, cross-linking study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1972
+	Hs
		807749 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		617932 H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		807817 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		241473 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		420812 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		807677 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		807743 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		807795 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		918628 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MINT_HUMAN (2-1787): 6.67e-46: 185: 7.93
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41		TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47
+	Hs
		1264778 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47
+	Hs
		1056847 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33
+	Hs
		1056919 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33
+	Hs
		1274405 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		ZN469_HUMAN (29-1459): 3.02e-23: 110: 9.99
+	Hs
		1224362 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		AGRG4_HUMAN (58-1397): 2.3e-15: 84.8: 13.13
+	Hs
		918773 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78