HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29643511
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 495
+	Hs
		829067 UBE2A_HUMAN (2-144): 1.41e-70: 210: 39.16		RAD18_HUMAN (1-495): 0: 695: 100.00
+	Hs
		927780 UBE2B_HUMAN (2-144): 5.71e-70: 209: 37.76		RAD18_HUMAN (1-495): 0: 695: 100.00
+	Mm
		1351596 UBE2A_MOUSE (2-144): 1.41e-70: 210: 39.16		RAD18_MOUSE (1-495): 0: 685: 65.36
+	Mm
		927792 UBE2B_MOUSE (2-144): 5.71e-70: 209: 37.76		RAD18_MOUSE (1-495): 0: 685: 65.36