Interactor 1: ODB2 (P53395)
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Gene: Dbt

Interactor 2: ODB2 (P53395)
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Gene: Dbt

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-oxoacid_dh~2-oxoacid_dh, 2-oxoacid_dh~Biotin_lipoyl, Biotin_lipoyl~Biotin_lipoyl, E3_binding~E3_binding
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0009083 - branched-chain amino acid catabolic process
GO:0015630 - microtubule cytoskeleton
GO:0031625 - ubiquitin protein ligase binding
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 482
Mm

1 482
+ Mm
+ At
+ Ce
+ At
+ Zm
+ Mm
+ Ec
+ At
+ Sc
+ Sc
+ Ss
+ At
+ Hs
+ At
+ Hs
+ Mp
+ Mm

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Last updated: 11Aug2025