Interactor 1: ODPX (Q8BKZ9)
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X)
Gene: Pdhx

Interactor 2: ODPX (Q8BKZ9)
Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X)
Gene: Pdhx

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-oxoacid_dh~2-oxoacid_dh, 2-oxoacid_dh~Biotin_lipoyl, Biotin_lipoyl~Biotin_lipoyl, E3_binding~E3_binding
Common GO terms GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005886 - plasma membrane
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 501
Mm

1 501
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ At
+ Ec
+ Zm
+ Mm
+ Sc
+ At
+ At
+ Ss
+ At
+ At

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Last updated: 11Aug2025