HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: Q53FC7 (Q53FC7)
Heat shock 70kDa protein 6 (HSP70B') variant
Gene: Q53FC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 643
+	Hs
		564054 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		503848 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		503846 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		483785 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HS71B_HUMAN (5-643): 0: 954: 81.85
+	Hs
		871525 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HSP72_HUMAN (3-643): 0: 945: 77.14
+	Hs
		871524 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		HSP72_HUMAN (3-643): 0: 945: 77.14
+	Hs
		504344 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Sc
		449898 GBB_YEAST (2-340): 1.33e-76: 243: 36.53		HSP73_YEAST (8-643): 0: 932: 70.43
+	Hs
		503817 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		564125 POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24		HSP76_HUMAN (1-643): 0: 990: 99.22
+	Hs
		714020 POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24		HS71L_HUMAN (1-643): 0: 981: 78.85
+	Hs
		504412 POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24		HSP7C_HUMAN (4-615): 0: 959: 78.76
+	Hs
		503614 LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17		HSP7C_HUMAN (4-615): 0: 959: 78.76