HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRI59 (Q8IWR1)
Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 104) (Tumor suppressor TSBF-1)
Gene: TRIM59

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25046164
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005813 - centrosome GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 403
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (1-352): 8.74e-78: 249: 16.15
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (2-353): 5.58e-67: 222: 15.63
+	Hs
		386629 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (1-352): 6.95e-66: 220: 15.00
+	Hs
		387458 P53_HUMAN (1-393): 0: 619: 100.00		TRIM2_HUMAN (5-336): 8.08e-60: 208: 18.29
+	Hs
		262148 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (5-336): 1.47e-58: 205: 19.25
+	Hs
		386960 P53_HUMAN (1-393): 0: 619: 100.00		TRI72_HUMAN (4-339): 4.25e-60: 203: 22.54
+	Hs
		387456 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (1-270): 7.42e-13: 71.6: 25.09
+	Hs
		387032 P53_HUMAN (1-393): 0: 619: 100.00		TRI69_HUMAN (7-269): 2.17e-12: 70.5: 26.50