HitPredict

Interactor 1: PGTB2 (P53611)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)
Gene: RABGGTB

Interactor 2: RAB7B (Q96AH8)
Ras-related protein Rab-7b
Gene: RAB7B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 199
+	Hs
		921527 PGTB2_HUMAN (1-331): 0: 523: 100.00		RAB8A_HUMAN (1-197): 4.42e-74: 223: 31.68
+	Hs
		921556 PGTB2_HUMAN (1-331): 0: 523: 100.00		RAB37_HUMAN (2-199): 7.27e-74: 223: 29.85
+	Hs
		901748 PGTB2_HUMAN (1-331): 0: 523: 100.00		RAB9A_HUMAN (9-199): 6.76e-46: 152: 42.64
+	Dm
		197128 Q9XZ68_DROME (22-330): 3.02e-156: 442: 64.42		O18332_DROME (2-199): 1.89e-76: 229: 34.80
+	Hs
		921572 PGTB2_HUMAN (1-331): 0: 523: 100.00		RAB9B_HUMAN (5-199): 2.56e-44: 147: 40.91
+	Sc
		376266 PGTB2_YEAST (17-327): 2.35e-146: 417: 51.89		YPT1_YEAST (1-199): 1.15e-75: 227: 33.01
+	Hs
		921519 PGTB1_HUMAN (18-323): 1.82e-117: 345: 28.99		RAB2B_HUMAN (5-197): 1.95e-84: 250: 34.69
+	Sc
		628314 PGTB2_YEAST (17-327): 2.35e-146: 417: 51.89		YPT7_YEAST (1-198): 4.64e-48: 157: 42.23