HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: ANK3 (Q12955)
Ankyrin-3 (ANK-3) (Ankyrin-G)
Gene: ANK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 4377
+	Hs
		950953 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		893947 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		900423 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		ANK3_HUMAN (1-4377): 0: 1944: 100.00
+	Hs
		925204 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ANK2_HUMAN (3012-4350): 1.52e-22: 110: 9.15