HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 821
+	Hs
		313492 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR1_HUMAN (1-820): 0: 772: 71.17
+	Hs
		313505 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR4_HUMAN (22-810): 0: 684: 55.86
+	Hs
		313518 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60
+	Hs
		313540 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		EPHA7_HUMAN (64-791): 2.59e-157: 486: 19.23
+	Hs
		313542 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43
+	Hs
		601538 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR2_HUMAN (1-821): 0: 863: 100.00
+	Hs
		508079 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR1_HUMAN (1-820): 0: 772: 71.17
+	Hs
		313488 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		CSF1R_HUMAN (467-753): 1.87e-78: 275: 43.11
+	Hs
		608024 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR4_HUMAN (22-810): 0: 684: 55.86
+	Hs
		665621 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHB2_HUMAN (9-766): 1.95e-166: 511: 17.58
+	Hs
		872668 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60
+	Hs
		872453 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA5_HUMAN (18-766): 3.48e-163: 502: 17.53
+	Hs
		1072532 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA7_HUMAN (64-791): 2.59e-157: 486: 19.23
+	Hs
		601507 MTMR3_HUMAN (196-777): 2.87e-71: 263: 13.18		FGFR2_HUMAN (1-821): 0: 863: 100.00
+	Hs
		609293 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		FGFR3_HUMAN (10-821): 0: 731: 65.69
+	Hs
		665422 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30
+	Hs
		385389 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		385054 RUFY3_HUMAN (138-584): 6.08e-63: 224: 11.45		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		159837 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		159845 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		CSF1R_HUMAN (467-753): 1.87e-78: 275: 43.11