HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006605 - protein targeting GO:0007165 - signal transduction GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1412
+	Hs
		909939 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		647208 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		683646 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		905018 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		982410 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		684283 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	At
		965369 14332_ARATH (3-239): 6.89e-143: 401: 65.15		CLV1_ARATH (120-582): 2.81e-64: 240: 18.82
+	At
		965375 14332_ARATH (3-239): 6.89e-143: 401: 65.15		BRL2_ARATH (238-852): 2.57e-49: 194: 10.20
+	At
		788683 14333_ARATH (3-239): 1.48e-141: 398: 64.73		BRL2_ARATH (238-852): 2.57e-49: 194: 10.20
+	Hs
		927034 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	At
		788442 14331_ARATH (3-238): 4.25e-142: 400: 64.58		EMS1_ARATH (360-811): 2.1e-40: 165: 11.33
+	At
		788640 14333_ARATH (3-239): 1.48e-141: 398: 64.73		EMS1_ARATH (360-811): 2.1e-40: 165: 11.33
+	Hs
		646881 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		683339 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		910166 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SHOC2_HUMAN (238-433): 1.01e-36: 149: 27.04
+	Hs
		683820 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SHOC2_HUMAN (238-433): 1.01e-36: 149: 27.04
+	Hs
		904552 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		982003 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Zm
		22560 B6U284_MAIZE (1-241): 1.06e-142: 401: 63.27		A0A1D6I257_MAIZE (396-696): 5.56e-12: 72.9: 9.84
+	Hs
		684030 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00