HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: DYLT1 (P63172)
Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog)
Gene: DYNLT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27173435, 35271311
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex GO:0030286 - dynein complex GO:0045505 - dynein intermediate chain binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 113
+	Hs
		928657 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00
+	Hs
		850526 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39
+	Hs
		928413 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09
+	Hs
		1262254 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09