HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 2752
+	Hs
		1346970 NLE1_HUMAN (8-106): 1.77e-21: 98.3: 10.58		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		997865 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1083355 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1083357 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		1074805 TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		903450 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Dm
		1099176 CAF1_DROME (226-419): 3.68e-29: 119: 18.36		Q9VT00_DROME (191-1774): 2.12e-45: 184: 9.95
+	Hs
		152663 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		1302927 NLE1_HUMAN (8-106): 1.77e-21: 98.3: 10.58		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		903375 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		820867 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Mm
		903669 WDR5_MOUSE (267-425): 7.48e-35: 133: 25.61		KMT2C_MOUSE (2097-2749): 1.31e-09: 66.6: 8.68
+	Hs
		903374 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152622 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152682 GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75