HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

Property	Details
Experiments	27173435, 33961781, 35271311, 24366813, 19615732, 24255178
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1084
+	Hs
		1119023 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		928379 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		1222261 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		928532 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		1291337 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		148656 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		928294 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85
+	Hs
		1051400 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DCTN1_HUMAN (510-863): 3.81e-09: 63.3: 14.85