Protein: LENG8
Leukocyte receptor cluster member 8

Gene: LENG8
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q96PV6

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1207334

PCID2
PCI domain-containing protein 2

2

7

High-throughput

0.783

High

954730

SEM1
26S proteasome complex subunit SEM1

2

3

Small-scale

0.737

High

478168

SNRPA
U1 small nuclear ribonucleoprotein A

4

6

High-throughput

0.704

High

786792

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

3

High-throughput

0.691

High

1198639

NCBP3
Nuclear cap-binding protein subunit 3

4

1

High-throughput

0.676

High

171917

ZN263
Zinc finger protein 263

2

1

High-throughput

0.628

High

1230893

Z324B
Zinc finger protein 324B

2

1

High-throughput

0.628

High

1397710

ZSC31
Zinc finger and SCAN domain-containing protein 31

2

2

High-throughput

0.628

High

1398052

ZN512
Zinc finger protein 512

2

2

High-throughput

0.628

High

1336565

MISSL
MAPK-interacting and spindle-stabilizing protein-like

3

6

High-throughput

0.613

High

928323

ATN1
Atrophin-1

2

9

High-throughput

0.613

High

384717

CRYAB
Alpha-crystallin B chain

2

5

High-throughput

0.611

High

772194

MSX2
Homeobox protein MSX-2

2

6

High-throughput

0.606

High

910638

HNRPM
Heterogeneous nuclear ribonucleoprotein M

2

4

High-throughput

0.606

High

1044699

ARI5A
AT-rich interactive domain-containing protein 5A

2

3

High-throughput

0.606

High

1061833

TLE5
TLE family member 5

2

2

High-throughput

0.606

High

1215006

INT11
Integrator complex subunit 11

2

3

High-throughput

0.606

High

1329085

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

2

6

High-throughput

0.606

High

1400247

TRAF4
TNF receptor-associated factor 4

2

6

High-throughput

0.606

High

1400273

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

1

High-throughput

0.606

High

1400276

MAGD1
Melanoma-associated antigen D1

2

5

High-throughput

0.606

High

1400278

NEMO
NF-kappa-B essential modulator

2

5

High-throughput

0.606

High

872001

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

1

High-throughput

0.604

High

995211

CSK2B
Casein kinase II subunit beta

2

1

High-throughput

0.601

High

1400272

ABT1
Activator of basal transcription 1

2

1

High-throughput

0.601

High

372890

MYC
Myc proto-oncogene protein

2

8

High-throughput

0.584

High

71139

VGLL3
Transcription cofactor vestigial-like protein 3

2

0

High-throughput

0.580

High

155177

SOCS7
Suppressor of cytokine signaling 7

2

0

High-throughput

0.580

High

176221

PER2
Period circadian protein homolog 2

2

0

High-throughput

0.580

High

347877

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.580

High

1081446

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

824297

RL13A
Large ribosomal subunit protein uL13

2

0

High-throughput

0.576

High

396747

ESR1
Estrogen receptor

2

16

High-throughput

0.571

High

1130656

GSE1
Genetic suppressor element 1

2

2

High-throughput

0.553

High

1133154

LASP1
LIM and SH3 domain protein 1

2

10

High-throughput

0.553

High

1137958

TNIP1
TNFAIP3-interacting protein 1

2

7

High-throughput

0.553

High

1206126

TGO1
Transport and Golgi organization protein 1 homolog

2

4

High-throughput

0.553

High

1367782

TFG
Protein TFG

2

8

High-throughput

0.553

High

1371411

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

5

High-throughput

0.553

High

1397859

CFA53
Cilia- and flagella-associated protein 53

2

4

High-throughput

0.553

High

1400268

HMGX4
HMG domain-containing protein 4

2

11

High-throughput

0.553

High

1086678

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.541

High

1400244

RHXF2
Rhox homeobox family member 2

1

6

High-throughput

0.541

High

1397906

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.536

High

191761

MAGB2
Melanoma-associated antigen B2

1

5

High-throughput

0.536

High

576511

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

4

High-throughput

0.536

High

785376

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

854236

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.536

High

905052

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.536

High

961211

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.536

High

1118132

DX39B
Spliceosome RNA helicase DDX39B

1

10

High-throughput

0.536

High

1160254

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

12

High-throughput

0.536

High

1291143

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1400258

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

2

High-throughput

0.536

High

1160554

SMN
Survival motor neuron protein

1

0

High-throughput

0.518

High

946860

H2B1D
Histone H2B type 1-D

1

16

High-throughput

0.515

High

1163149

H2B2E
Histone H2B type 2-E

1

16

High-throughput

0.515

High

415800

HSPB1
Heat shock protein beta-1

1

5

High-throughput

0.515

High

1289876

Q86V38
Atrophin 1

1

6

High-throughput

0.515

High

244759

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.513

High

929329

OAZ1
Ornithine decarboxylase antizyme 1

1

0

High-throughput

0.513

High

1281447

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1294348

ZN677
Zinc finger protein 677

1

0

High-throughput

0.513

High

1400241

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.513

High

1400245

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

0

High-throughput

0.513

High

1400271

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

162664

ANM5
Protein arginine N-methyltransferase 5

1

6

High-throughput

0.508

High

216520

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

1

High-throughput

0.508

High

246876

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.508

High

1396917

ANM6
Protein arginine N-methyltransferase 6

1

6

High-throughput

0.508

High

1400275

PYGO1
Pygopus homolog 1

1

6

High-throughput

0.494

High

657290

KALM
Anosmin-1

1

5

High-throughput

0.489

High

718452

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

833162

MNDA
Myeloid cell nuclear differentiation antigen

1

3

High-throughput

0.489

High

859955

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.489

High

1063843

LG3BP
Galectin-3-binding protein

1

2

High-throughput

0.489

High

1248391

I27RA
Interleukin-27 receptor subunit alpha

1

6

High-throughput

0.489

High

1331843

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

1340443

DDX55
ATP-dependent RNA helicase DDX55

1

3

High-throughput

0.489

High

1398989

ODAD4
Outer dynein arm-docking complex subunit 4

1

3

High-throughput

0.489

High

1400251

WDR55
WD repeat-containing protein 55

1

9

High-throughput

0.489

High

1400260

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

9

High-throughput

0.489

High

1400265

RGL1
Ral guanine nucleotide dissociation stimulator-like 1

1

1

High-throughput

0.489

High

1400277

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.489

High

1332928

SMYD1
Histone-lysine N-methyltransferase SMYD1

1

0

High-throughput

0.486

High

1400253

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.481

High

129346

MEN1
Menin

1

3

High-throughput

0.479

High

130583

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

143202

NFIB
Nuclear factor 1 B-type

1

7

High-throughput

0.479

High

401327

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

406531

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.479

High

474223

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.479

High

485351

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

High-throughput

0.479

High

520304

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

697225

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

765812

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.479

High

766775

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

831270

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

887140

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

979152

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.479

High

1024775

VIGLN
Vigilin

1

5

High-throughput

0.479

High

1087958

NFIA
Nuclear factor 1 A-type

1

11

High-throughput

0.479

High

1121728

SAFB2
Scaffold attachment factor B2

1

7

High-throughput

0.479

High

1128090

DHX8
ATP-dependent RNA helicase DHX8

1

3

High-throughput

0.479

High

1217013

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

2

Small-scale

0.479

High

1276661

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1289547

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1290662

ZCH18
Zinc finger CCCH domain-containing protein 18

1

8

High-throughput

0.479

High

1313352

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1329819

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.479

High

1351131

SP7
Transcription factor Sp7

1

6

High-throughput

0.479

High

1367062

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

1387504

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

7

High-throughput

0.479

High

1400242

FEV
Protein FEV

1

2

High-throughput

0.479

High

1400248

KLF16
Krueppel-like factor 16

1

7

High-throughput

0.479

High

1400252

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1400256

BRD7
Bromodomain-containing protein 7

1

7

High-throughput

0.479

High

1400257

RNC
Ribonuclease 3

1

6

High-throughput

0.479

High

1400263

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

1400264

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

1400267

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1400274

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

85457

B7ZLH0
FAM22F protein

1

1

High-throughput

0.470

High

246107

KIF1B
Kinesin-like protein KIF1B

1

4

High-throughput

0.470

High

570566

GFAP
Glial fibrillary acidic protein

1

3

High-throughput

0.470

High

954586

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.470

High

1310079

Q8IWG5
ANKHD1 protein

1

6

High-throughput

0.470

High

1360729

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1315910

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.460

High

643995

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

1032221

EXOSX
Exosome complex component 10

1

0

High-throughput

0.458

High

1363948

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1400259

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1400261

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

1400262

AATF
Protein AATF

1

0

High-throughput

0.458

High

1056914

FMR1
Fragile X messenger ribonucleoprotein 1

1

9

High-throughput

0.457

High

480275

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.445

High

1130397

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

1220504

BTBD8
BTB/POZ domain-containing protein 8

1

2

High-throughput

0.445

High

51330

NTM2F
NUT family member 2F

1

1

High-throughput

0.439

High

1311383

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

2

High-throughput

0.439

High

141059

NOP56
Nucleolar protein 56

1

1

High-throughput

0.437

High

302930

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

13

High-throughput

0.437

High

768934

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

984916

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.437

High

995776

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.437

High

1118761

KLF5
Krueppel-like factor 5

1

7

High-throughput

0.437

High

1141877

EEA1
Early endosome antigen 1

1

6

High-throughput

0.437

High

1229043

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.437

High

1256921

SEML
Putative protein SEM1, isoform 2

1

2

High-throughput

0.437

High

1311837

DHX40
Probable ATP-dependent RNA helicase DHX40

1

3

High-throughput

0.437

High

1339142

NUP35
Nucleoporin NUP35

1

3

High-throughput

0.437

High

1400249

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

4

High-throughput

0.437

High

1400250

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1400255

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

4

High-throughput

0.437

High

1400270

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.437

High

1400266

TAP26
Thyroid transcription factor 1-associated protein 26

2

0

High-throughput

0.328

High

70431

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

70931

CMI2B
Ciliary microtubule inner protein 2B

2

0

High-throughput

0.316

High

1131890

COG2
Conserved oligomeric Golgi complex subunit 2

2

0

High-throughput

0.316

High

1211143

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1350970

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

1400243

TS101
Tumor susceptibility gene 101 protein

2

0

High-throughput

0.316

High

1340321

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.299

High

290685

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

329963

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.279

Low

711586

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

1356724

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

1384510

SKA1
SKA complex subunit 1

1

0

High-throughput

0.279

Low

1400246

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1400254

PROK2
Prokineticin-2

1

0

High-throughput

0.279

Low

1400269

NRBP
Nuclear receptor-binding protein

1

0

High-throughput

0.279

Low

301646

WFS1
Wolframin

1

0

High-throughput

0.268

Low

622251

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025