HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: WDR44 (Q5JSH3)
WD repeat-containing protein 44 (Rab11-binding protein) (Rab11BP) (Rabphilin-11)
Gene: WDR44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 913
+	Hs
		891822 ACTB_HUMAN (1-375): 0: 604: 98.93		WDR44_HUMAN (1-913): 0: 589: 100.00
+	Mm
		892203 ACTB_MOUSE (1-375): 0: 604: 98.93		AHI1_MOUSE (580-883): 1.91e-74: 266: 24.69
+	Hs
		903280 ACTBL_HUMAN (2-375): 0: 734: 91.44		WDR5_HUMAN (816-912): 5.98e-19: 91: 11.88
+	Hs
		903316 POTEE_HUMAN (1-375): 0: 729: 91.47		WDR5_HUMAN (816-912): 5.98e-19: 91: 11.88
+	Hs
		932318 ACTC_HUMAN (2-375): 0: 595: 94.39		SNR40_HUMAN (721-913): 8.12e-35: 138: 13.13
+	Hs
		891660 ACTB_HUMAN (1-375): 0: 604: 98.93		WDR5_HUMAN (816-912): 5.98e-19: 91: 11.88
+	Hs
		903110 ACTG_HUMAN (1-375): 0: 604: 100.00		WDR5_HUMAN (816-912): 5.98e-19: 91: 11.88
+	Hs
		792947 ACTB_HUMAN (1-375): 0: 604: 98.93		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		792968 ACTG_HUMAN (1-375): 0: 604: 100.00		LIS1_HUMAN (818-912): 3.83e-16: 83.7: 16.16
+	Hs
		921519 ACTS_HUMAN (2-375): 0: 594: 93.85		GBB2_HUMAN (778-911): 6.81e-17: 84.9: 12.68
+	Hs
		892126 ACTB_HUMAN (1-375): 0: 604: 98.93		FBW1A_HUMAN (826-911): 6.76e-11: 67.9: 7.96
+	Hs
		933074 ACTS_HUMAN (2-375): 0: 594: 93.85		FBW1A_HUMAN (826-911): 6.76e-11: 67.9: 7.96