HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26369384
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 514
+	Hs
		849435 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TBL1R_HUMAN (1-514): 1.37e-162: 472: 100.00
+	Hs
		1282344 UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77		TBL1R_HUMAN (1-514): 1.37e-162: 472: 100.00
+	Hs
		245581 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245589 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		245625 UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Hs
		895800 UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07		SMU1_HUMAN (329-513): 4.3e-39: 150: 19.00
+	Hs
		930227 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		TAF5_HUMAN (164-376): 6.23e-14: 76.6: 23.72