Interactor 1: D3ZV15 (D3ZV15)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl
Interactor 2: IRS1 (P35570)
Insulin receptor substrate 1 (IRS-1) (pp185)
Gene: IRS1
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19546233 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001784 - phosphotyrosine residue binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0014823 - response to activity GO:0019901 - protein kinase binding and 2 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
