HitPredict

Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19013454
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 363 Hs			1 389
+	Rn
		1195211 RD23B_RAT (3-363): 5.22e-107: 321: 52.05		Q6PCT9_RAT (1-389): 2.31e-136: 396: 97.94
+	Hs
		931663 RD23B_HUMAN (3-363): 2.98e-104: 314: 54.03		PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00
+	Dm
		1463472 Q9V3W9_DROME (3-362): 2.29e-85: 266: 38.19		PSMD6_DROME (1-389): 2.37e-125: 368: 70.18
+	Hs
		127910 RD23A_HUMAN (1-363): 3.22e-117: 345: 100.00		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Hs
		1136619 UBQL1_HUMAN (2-312): 1.52e-47: 171: 14.47		PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00
+	Rn
		81566 RD23B_RAT (3-363): 5.22e-107: 321: 52.05		B5DEP6_RAT (3-387): 3.09e-77: 246: 11.03
+	Hs
		1136613 UBQL2_HUMAN (2-312): 4.48e-45: 165: 16.08		PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00
+	Hs
		1136605 UBQL4_HUMAN (3-312): 1.49e-44: 163: 15.87		PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00
+	Hs
		127911 RD23B_HUMAN (3-363): 2.98e-104: 314: 54.03		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Sc
		744018 RAD23_YEAST (3-361): 1.04e-74: 238: 28.57		RPN7_YEAST (11-389): 3.43e-86: 269: 35.47
+	Hs
		987030 RS27A_HUMAN (3-93): 2.91e-16: 77.1: 27.47		PSMD6_HUMAN (1-389): 5.6e-137: 397: 100.00
+	Sc
		744029 RAD23_YEAST (3-361): 1.04e-74: 238: 28.57		RPN6_YEAST (30-389): 1.54e-56: 192: 12.57
+	Hs
		128080 UBQL1_HUMAN (2-312): 1.52e-47: 171: 14.47		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Hs
		128076 UBQL2_HUMAN (2-312): 4.48e-45: 165: 16.08		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Hs
		128072 UBQL4_HUMAN (3-312): 1.49e-44: 163: 15.87		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Hs
		949459 UBQL2_HUMAN (2-312): 4.48e-45: 165: 16.08		EIF3E_HUMAN (26-387): 7.74e-74: 238: 14.04
+	Hs
		127928 RL40_HUMAN (3-129): 3.34e-38: 134: 22.84		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03
+	Hs
		127927 RS27A_HUMAN (3-93): 2.91e-16: 77.1: 27.47		PSD11_HUMAN (3-387): 8.58e-77: 245: 11.03