HitPredict

Interactor 1: PSMD6 (Q9V3G7)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (Protein Rpn7)
Gene: Rpn7

Interactor 2: Q9V3W9 (Q9V3W9)
UV excision repair protein RAD23
Gene: Rad23

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22364263
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 389 Dm			1 414
+	Rn
		1195211 Q6PCT9_RAT (1-389): 4.99e-143: 413: 69.67		RD23B_RAT (1-414): 8.99e-95: 292: 35.64
+	Hs
		931663 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		RD23B_HUMAN (1-414): 2.59e-90: 280: 34.97
+	Hs
		931519 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		RD23A_HUMAN (3-414): 2.18e-82: 258: 37.89
+	Hs
		1136560 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		DDI1_HUMAN (1-339): 4.38e-52: 180: 11.49
+	Hs
		1136535 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		DDI2_HUMAN (1-361): 8.86e-40: 148: 11.84
+	Rn
		81566 B5DEP6_RAT (3-388): 3.81e-83: 261: 13.53		RD23B_RAT (1-414): 8.99e-95: 292: 35.64
+	Hs
		127911 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RD23B_HUMAN (1-414): 2.59e-90: 280: 34.97
+	Hs
		987030 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		RS27A_HUMAN (1-86): 1.92e-31: 119: 31.40
+	Dm
		1463491 PSMD6_DROME (1-389): 6.74e-134: 390: 100.00		Q9VWD9_DROME (1-406): 6.51e-35: 137: 10.24
+	Sc
		744018 RPN7_YEAST (15-389): 8.24e-95: 291: 33.83		RAD23_YEAST (2-413): 1.1e-72: 234: 24.83
+	Hs
		127910 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RD23A_HUMAN (3-414): 2.18e-82: 258: 37.89
+	Hs
		1136619 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		UBQL1_HUMAN (206-410): 2.75e-15: 79.6: 14.29
+	Hs
		1136605 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		UBQL4_HUMAN (95-410): 8.41e-15: 78.1: 13.57
+	Hs
		1136613 PSMD6_HUMAN (1-389): 1.38e-143: 414: 70.18		UBQL2_HUMAN (87-410): 5.26e-13: 72.7: 16.46
+	Hs
		128026 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		DDI1_HUMAN (1-339): 4.38e-52: 180: 11.49
+	Hs
		127993 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		DDI2_HUMAN (1-361): 8.86e-40: 148: 11.84
+	Hs
		127928 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RL40_HUMAN (1-83): 1.81e-34: 126: 30.12
+	Hs
		127927 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		RS27A_HUMAN (1-86): 1.92e-31: 119: 31.40
+	Hs
		128072 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		UBQL4_HUMAN (95-410): 8.41e-15: 78.1: 13.57
+	Hs
		128076 PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53		UBQL2_HUMAN (87-410): 5.26e-13: 72.7: 16.46