Protein: RPN7
26S proteasome regulatory subunit RPN7

Gene: RPN7
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: Q06103

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005198 - structural molecule activity
GO:0005634 - nucleus
GO:0005838 - proteasome regulatory particle
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817092

RPN3
26S proteasome regulatory subunit RPN3

11

16

Small-scale

0.979

High

1053600

RPN6
26S proteasome regulatory subunit RPN6

11

18

Small-scale

0.975

High

738341

RPN12
26S proteasome regulatory subunit RPN12

10

4

Small-scale

0.975

High

1053599

RPN5
26S proteasome regulatory subunit RPN5

10

20

Small-scale

0.974

High

314910

SEM1
26S proteasome complex subunit SEM1

10

1

Small-scale

0.972

High

751007

PRS7
26S proteasome regulatory subunit 7 homolog

7

20

Small-scale

0.962

High

1033891

PRS8
26S proteasome regulatory subunit 8 homolog

6

20

High-throughput

0.947

High

750896

PRS6B
26S proteasome regulatory subunit 6B homolog

5

20

High-throughput

0.925

High

1053594

RPN8
26S proteasome regulatory subunit RPN8

5

20

High-throughput

0.925

High

1044969

RPN9
26S proteasome regulatory subunit RPN9

4

20

High-throughput

0.900

High

822438

PRS4
26S proteasome regulatory subunit 4 homolog

4

20

Small-scale

0.896

High

750783

PRS6A
26S proteasome regulatory subunit 6A

4

20

High-throughput

0.892

High

921105

PRS10
26S proteasome subunit RPT4

3

20

High-throughput

0.855

High

850211

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

26

20

Small-scale

0.767

High

803692

RPN1
26S proteasome regulatory subunit RPN1

8

18

Small-scale

0.748

High

806820

RPN10
26S proteasome regulatory subunit RPN10

7

5

Small-scale

0.747

High

740226

RPN2
26S proteasome regulatory subunit RPN2

5

17

High-throughput

0.716

High

645209

PSB4
Proteasome subunit beta type-4

4

20

Small-scale

0.683

High

918107

RPN14
26S proteasome regulatory subunit RPN14

3

5

High-throughput

0.667

High

850350

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

3

4

High-throughput

0.657

High

803169

ECM29
Proteasome component ECM29

3

3

High-throughput

0.656

High

822021

PSA4
Proteasome subunit alpha type-4

3

20

High-throughput

0.656

High

893077

PSD10
Probable 26S proteasome regulatory subunit p28

3

4

Small-scale

0.656

High

509724

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

16

High-throughput

0.647

High

680074

CDC48
Cell division control protein 48

1

3

High-throughput

0.618

High

727317

HS104
Heat shock protein 104

1

3

High-throughput

0.618

High

744018

RAD23
UV excision repair protein RAD23

1

20

High-throughput

0.618

High

1053591

RPN7
26S proteasome regulatory subunit RPN7

1

17

High-throughput

0.618

High

798574

HSM3
DNA mismatch repair protein HSM3

2

1

Small-scale

0.612

High

150310

RPN13
26S proteasome regulatory subunit RPN13

2

1

High-throughput

0.611

High

661439

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.584

High

661562

PSA2
Proteasome subunit alpha type-2

2

20

High-throughput

0.584

High

671137

SIS1
Protein SIS1

2

1

High-throughput

0.584

High

924462

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

2

5

Small-scale

0.584

High

393353

HSP82
ATP-dependent molecular chaperone HSP82

2

3

High-throughput

0.571

High

925060

APJ1
J domain-containing protein APJ1

2

3

High-throughput

0.571

High

616453

SEC18
Vesicular-fusion protein SEC18

1

5

High-throughput

0.553

High

527710

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.552

High

546329

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

742427

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.536

High

836102

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.536

High

580089

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.533

High

1043568

ESC1
Silent chromatin protein ESC1

2

1

High-throughput

0.533

High

416917

CDC25
Cell division control protein 25

1

0

High-throughput

0.518

High

752751

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.514

High

518130

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.501

High

738077

MKK2
MAP kinase kinase MKK2/SSP33

1

4

High-throughput

0.489

High

797995

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.489

High

1053603

DUF1
DUB-associated factor 1

1

3

High-throughput

0.489

High

863952

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

1

High-throughput

0.481

High

435369

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

603109

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

636689

PSA1
Proteasome subunit alpha type-1

1

20

High-throughput

0.479

High

668411

PSB2
Proteasome subunit beta type-2

1

20

High-throughput

0.479

High

708222

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

721331

PSB7
Proteasome subunit beta type-7

1

20

High-throughput

0.479

High

735959

PSA5
Proteasome subunit alpha type-5

1

20

High-throughput

0.479

High

737947

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

738928

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

776649

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

779350

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.479

High

792253

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

800862

PSB1
Proteasome subunit beta type-1

1

20

High-throughput

0.479

High

821990

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.479

High

826323

PSMD9
Probable 26S proteasome regulatory subunit p27

1

4

Small-scale

0.479

High

1042236

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

1044462

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

1053592

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

764008

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

814988

PTI1
Protein PTI1

1

0

High-throughput

0.458

High

826844

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

923308

DUS1
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]

1

0

High-throughput

0.458

High

1053597

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

525191

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

819836

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

383898

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

513224

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

795543

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.437

High

802391

RS20
Small ribosomal subunit protein uS10

1

1

Small-scale

0.437

High

874534

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

877910

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

1033571

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

1053598

ATG9
Autophagy-related protein 9

1

3

High-throughput

0.437

High

1053601

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.437

High

865963

DPH4
Diphthamide biosynthesis protein 4

1

0

High-throughput

0.426

High

1053602

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.426

High

671715

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

575614

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.279

Low

793280

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

0

High-throughput

0.269

Low

844323

SPG5
Stationary phase protein 5

1

0

High-throughput

0.269

Low

737046

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

817764

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

1053593

LEC1
PX domain-containing protein LEC1

1

0

Small-scale

0.251

Low

436177

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

512660

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

864829

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

1053595

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

1053596

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025