HitPredict

Interactor 1: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.853

Property	Details
Experiments	18158899, 31263106, 20595233
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 914 Sc			1 136
+	Sc
		444866 SIR3_YEAST (1-914): 0: 587: 26.50		H3_YEAST (1-136): 1.85e-55: 171: 100.00
+	Sc
		444847 SIR3_YEAST (1-914): 0: 587: 26.50		CENPA_YEAST (24-134): 1.34e-40: 136: 53.04
+	Hs
		231466 ORC4_HUMAN (443-840): 4.21e-80: 268: 13.51		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		231468 ORC4_HUMAN (443-840): 4.21e-80: 268: 13.51		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		231486 ORC4_HUMAN (443-840): 4.21e-80: 268: 13.51		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Zm
		16799 A0A1D6GQ42_MAIZE (420-688): 1.21e-26: 119: 11.68		B6SIV8_MAIZE (1-136): 3.37e-59: 181: 87.50
+	Hs
		934464 TERA_HUMAN (420-667): 3.73e-25: 114: 10.00		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		188475 NVL_HUMAN (333-647): 1.08e-20: 100: 13.68		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		769968 RFC1_HUMAN (147-633): 9.82e-20: 97.4: 12.66		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		769970 RFC1_HUMAN (147-633): 9.82e-20: 97.4: 12.66		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		769946 RFC1_HUMAN (147-633): 9.82e-20: 97.4: 12.66		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73