HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1025
+	Hs
		891851 ACTB_HUMAN (4-377): 0: 599: 94.12		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		892089 ACTB_HUMAN (4-377): 0: 599: 94.12		SWP70_HUMAN (370-824): 7.27e-58: 212: 19.22
+	Hs
		929935 ACTG_HUMAN (4-377): 0: 599: 94.39		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		929898 ACTG_HUMAN (4-377): 0: 599: 94.39		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		932211 ACTC_HUMAN (1-377): 0: 599: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		148662 ACTC_HUMAN (1-377): 0: 599: 100.00		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 599: 94.12		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Rn
		892228 ACTB_RAT (4-377): 0: 599: 94.12		MYH9_RAT (566-1025): 4.61e-18: 92.5: 9.81
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 599: 94.12		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 599: 94.39		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 599: 98.94		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Rn
		892236 ACTB_RAT (4-377): 0: 599: 94.12		MYH10_RAT (534-1014): 1.07e-15: 84.8: 11.32
+	Hs
		725135 ACTH_HUMAN (4-377): 0: 591: 98.93		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		929869 ACTG_HUMAN (4-377): 0: 599: 94.39		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		932171 ACTC_HUMAN (1-377): 0: 599: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		255307 ACTB_HUMAN (4-377): 0: 599: 94.12		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Mm
		930101 ACTH_MOUSE (4-377): 0: 591: 98.93		PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60