HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: TACC3 (Q9Y6A5)
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
Gene: TACC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 838
+	Hs
		1175284 TBA1A_HUMAN (1-440): 0: 715: 99.55		TACC3_HUMAN (1-838): 3.74e-96: 321: 100.00
+	Hs
		934041 TBB4B_HUMAN (1-437): 0: 697: 40.96		TACC3_HUMAN (1-838): 3.74e-96: 321: 100.00
+	Hs
		1175288 TBA1A_HUMAN (1-440): 0: 715: 99.55		R4GMT7_HUMAN (127-678): 6.37e-45: 173: 19.12
+	Hs
		264032 TBA1B_HUMAN (1-440): 0: 717: 100.00		TACC1_HUMAN (127-837): 2.57e-36: 149: 26.70
+	Hs
		264059 TBA1A_HUMAN (1-440): 0: 715: 99.55		TACC1_HUMAN (127-837): 2.57e-36: 149: 26.70
+	Hs
		311802 TBA1B_HUMAN (1-440): 0: 717: 100.00		TACC2_HUMAN (74-837): 4.81e-35: 146: 20.10
+	Hs
		933807 TBB4B_HUMAN (1-437): 0: 697: 40.96		DCTN1_HUMAN (515-836): 6.94e-39: 158: 16.86
+	Hs
		92367 TBA1A_HUMAN (1-440): 0: 715: 99.55		E9PBC6_HUMAN (74-837): 1.75e-30: 132: 19.22
+	Hs
		264033 TBB4B_HUMAN (1-437): 0: 697: 40.96		TACC1_HUMAN (127-837): 2.57e-36: 149: 26.70
+	Hs
		311803 TBB4B_HUMAN (1-437): 0: 697: 40.96		TACC2_HUMAN (74-837): 4.81e-35: 146: 20.10