Protein: PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H (Phosphatidylinositol-glycan biosynthesis class H protein) (PIG-H)

Gene: PIGH
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q14442

Gene Ontology (top 5):
GO:0000506 - glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0003824 - catalytic activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

790153

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

4

0

Small-scale

0.660

High

1126352

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

3

0

Small-scale

0.646

High

943440

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

2

0

High-throughput

0.602

High

1126389

S27A6
Long-chain fatty acid transport protein 6

2

5

High-throughput

0.601

High

1126324

UBAC2
Ubiquitin-associated domain-containing protein 2

2

0

High-throughput

0.576

High

1126301

TM63B
Mechanosensitive cation channel TMEM63B

2

1

High-throughput

0.549

High

171453

S27A2
Long-chain fatty acid transport protein 2

1

5

High-throughput

0.536

High

297055

DHRS3
Short-chain dehydrogenase/reductase 3

1

2

High-throughput

0.536

High

596651

NCPR
NADPH--cytochrome P450 reductase

1

1

High-throughput

0.536

High

617303

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

1

High-throughput

0.536

High

643360

OSBP1
Oxysterol-binding protein 1

1

2

High-throughput

0.536

High

787871

SRBP1
Sterol regulatory element-binding protein 1

1

1

High-throughput

0.536

High

1023335

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

1043123

TAP1
Antigen peptide transporter 1

1

2

High-throughput

0.536

High

1043206

TAP2
Antigen peptide transporter 2

1

2

High-throughput

0.536

High

1085422

SRBP2
Sterol regulatory element-binding protein 2

1

1

High-throughput

0.536

High

1111534

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.536

High

1126292

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.536

High

1126298

S27A3
Long-chain fatty acid transport protein 3

1

5

High-throughput

0.536

High

1126310

S27A4
Long-chain fatty acid transport protein 4

1

5

High-throughput

0.536

High

1126311

S27A1
Long-chain fatty acid transport protein 1

1

5

High-throughput

0.536

High

1126320

RDH10
Retinol dehydrogenase 10

1

3

High-throughput

0.536

High

1126334

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.536

High

1126340

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.536

High

1126341

P121A
Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.536

High

1126350

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

1

High-throughput

0.536

High

1126362

OSBL8
Oxysterol-binding protein-related protein 8

1

2

High-throughput

0.536

High

1126363

OSBL5
Oxysterol-binding protein-related protein 5

1

2

High-throughput

0.536

High

1126368

AT131
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.536

High

1126376

DJB12
DnaJ homolog subfamily B member 12

1

1

High-throughput

0.536

High

1126379

TM63C
Osmosensitive cation channel TMEM63C

1

1

High-throughput

0.536

High

1126380

STIM2
Stromal interaction molecule 2

1

1

High-throughput

0.536

High

1126381

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.536

High

1126392

DHRS7
Dehydrogenase/reductase SDR family member 7

1

2

High-throughput

0.536

High

50553

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.513

High

61107

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

139095

FAAH1
Fatty-acid amide hydrolase 1

1

0

High-throughput

0.513

High

184986

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.513

High

191217

TLR3
Toll-like receptor 3

1

0

High-throughput

0.513

High

319760

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

337728

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.513

High

399684

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

0

High-throughput

0.513

High

450238

HYEP
Epoxide hydrolase 1

1

0

High-throughput

0.513

High

611119

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.513

High

690249

STOM
Stomatin

1

0

High-throughput

0.513

High

833499

PTGDS
Prostaglandin-H2 D-isomerase

1

0

High-throughput

0.513

High

1023412

AT11A
Phospholipid-transporting ATPase IH

1

0

High-throughput

0.513

High

1047541

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.513

High

1091923

SEC20
Vesicle transport protein SEC20

1

0

High-throughput

0.513

High

1097773

STX5
Syntaxin-5

1

0

High-throughput

0.513

High

1103535

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.513

High

1110786

PKD2
Polycystin-2

1

0

High-throughput

0.513

High

1125428

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.513

High

1126287

ERG1
Squalene monooxygenase

1

0

High-throughput

0.513

High

1126288

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.513

High

1126290

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

1126293

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.513

High

1126303

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.513

High

1126305

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

0

High-throughput

0.513

High

1126306

CP4FN
Ultra-long-chain fatty acid omega-hydroxylase

1

0

High-throughput

0.513

High

1126307

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.513

High

1126308

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.513

High

1126312

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

1126313

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.513

High

1126314

TMC6
Transmembrane channel-like protein 6

1

0

High-throughput

0.513

High

1126317

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.513

High

1126318

VRK2
Serine/threonine-protein kinase VRK2

1

0

High-throughput

0.513

High

1126319

ZDH13
Palmitoyltransferase ZDHHC13

1

0

High-throughput

0.513

High

1126321

GHDC
GH3 domain-containing protein

1

0

High-throughput

0.513

High

1126322

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.513

High

1126326

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1126327

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.513

High

1126331

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.513

High

1126335

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1126337

ASTRA
Protein Aster-A

1

0

High-throughput

0.513

High

1126338

FAF2
FAS-associated factor 2

1

0

High-throughput

0.513

High

1126343

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.513

High

1126346

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

0

High-throughput

0.513

High

1126349

CIB1
Calcium and integrin-binding protein 1

1

0

High-throughput

0.513

High

1126353

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.513

High

1126355

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.513

High

1126367

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.513

High

1126371

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.513

High

1126375

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.513

High

1126385

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.513

High

1126386

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.513

High

1126394

TBL2
Transducin beta-like protein 2

1

0

High-throughput

0.513

High

1126398

TX264
Testis-expressed protein 264

1

0

High-throughput

0.513

High

76113

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.489

High

190608

MRP4
ATP-binding cassette sub-family C member 4

1

2

High-throughput

0.489

High

243798

ADCY3
Adenylate cyclase type 3

1

1

High-throughput

0.489

High

320975

SUN1
SUN domain-containing protein 1

1

1

High-throughput

0.489

High

690089

AVR2A
Activin receptor type-2A

1

2

High-throughput

0.489

High

787164

BMR1A
Bone morphogenetic protein receptor type-1A

1

2

High-throughput

0.489

High

787298

ACV1B
Activin receptor type-1B

1

2

High-throughput

0.489

High

907672

CLCN2
Chloride channel protein 2

1

1

High-throughput

0.489

High

907708

CLCN3
H(+)/Cl(-) exchange transporter 3

1

1

High-throughput

0.489

High

908307

ADCY7
Adenylate cyclase type 7

1

1

High-throughput

0.489

High

933402

S12A2
Solute carrier family 12 member 2

1

4

High-throughput

0.489

High

1126302

MRP7
ATP-binding cassette sub-family C member 10

1

3

High-throughput

0.489

High

1126333

MRP2
ATP-binding cassette sub-family C member 2

1

2

High-throughput

0.489

High

1126366

AT133
Polyamine-transporting ATPase 13A3

1

3

High-throughput

0.489

High

1126369

AT132
Polyamine-transporting ATPase 13A2

1

4

High-throughput

0.489

High

1126372

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

1

High-throughput

0.489

High

1126378

MYOF
Myoferlin

1

1

High-throughput

0.489

High

1126382

SUN2
SUN domain-containing protein 2

1

1

High-throughput

0.489

High

1126383

S12A6
Solute carrier family 12 member 6

1

4

High-throughput

0.489

High

1126387

S12A4
Solute carrier family 12 member 4

1

4

High-throughput

0.489

High

1126397

S12A7
Solute carrier family 12 member 7

1

4

High-throughput

0.489

High

1126351

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

1126342

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.445

High

1126388

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.445

High

1126390

S27A5
Long-chain fatty acid transport protein 5

1

5

High-throughput

0.445

High

317065

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

Small-scale

0.426

High

1126300

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.426

High

1126332

PIGC
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

1

0

Small-scale

0.426

High

1126336

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.426

High

753809

MRP1
Multidrug resistance-associated protein 1

1

2

High-throughput

0.407

High

1126294

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

2

High-throughput

0.407

High

1126358

S12A9
Solute carrier family 12 member 9

1

4

High-throughput

0.407

High

1126360

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

2

High-throughput

0.407

High

1126399

S4A7
Sodium bicarbonate cotransporter 3

1

2

High-throughput

0.407

High

1126345

P2RX4
P2X purinoceptor 4

3

0

High-throughput

0.347

High

332122

I18RA
Interleukin-18 receptor accessory protein

2

0

High-throughput

0.328

High

1126296

ANO6
Anoctamin-6

2

0

High-throughput

0.313

High

1126347

OSMR
Oncostatin-M-specific receptor subunit beta

2

0

High-throughput

0.313

High

127677

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.279

Low

175367

PLXB2
Plexin-B2

1

0

High-throughput

0.279

Low

273527

DJC13
DnaJ homolog subfamily C member 13

1

0

High-throughput

0.279

Low

322726

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.279

Low

359814

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

410841

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.279

Low

559954

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.279

Low

560391

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.279

Low

720223

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.279

Low

725384

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

0

High-throughput

0.279

Low

907239

ARSL
Arylsulfatase L

1

0

High-throughput

0.279

Low

944944

RAB38
Ras-related protein Rab-38

1

0

High-throughput

0.279

Low

1063246

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.279

Low

1086465

KCNH2
Voltage-gated inwardly rectifying potassium channel KCNH2

1

0

High-throughput

0.279

Low

1110240

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.279

Low

1126291

TRIPB
Thyroid receptor-interacting protein 11

1

0

High-throughput

0.279

Low

1126295

IPIL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2

1

0

High-throughput

0.279

Low

1126297

FND3B
Fibronectin type III domain-containing protein 3B

1

0

High-throughput

0.279

Low

1126299

TM201
Transmembrane protein 201

1

0

High-throughput

0.279

Low

1126309

ZNT6
Zinc transporter 6

1

0

High-throughput

0.279

Low

1126315

FRMD5
FERM domain-containing protein 5

1

0

High-throughput

0.279

Low

1126316

T200A
Transmembrane protein 200A

1

0

High-throughput

0.279

Low

1126323

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

1

0

High-throughput

0.279

Low

1126328

MZB1
Marginal zone B- and B1-cell-specific protein

1

0

High-throughput

0.279

Low

1126329

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

1126330

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.279

Low

1126344

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.279

Low

1126354

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

0

High-throughput

0.279

Low

1126356

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.279

Low

1126357

CA043
Protein C1orf43

1

0

High-throughput

0.279

Low

1126361

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

1126364

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.279

Low

1126365

PCX3
Pecanex-like protein 3

1

0

High-throughput

0.279

Low

1126370

AAAS
Aladin

1

0

High-throughput

0.279

Low

1126373

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.279

Low

1126377

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.279

Low

1126384

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.279

Low

1126391

MAN1
Inner nuclear membrane protein Man1

1

0

High-throughput

0.279

Low

1126393

C2CD2
C2 domain-containing protein 2

1

0

High-throughput

0.279

Low

1126395

PCDGL
Protocadherin gamma-C4

1

0

High-throughput

0.279

Low

1126396

SNX14
Sorting nexin-14

1

0

High-throughput

0.279

Low

1126348

THIOM
Thioredoxin, mitochondrial

1

0

High-throughput

0.238

Low

257631

PRAF2
PRA1 family protein 2

1

0

High-throughput

0.232

Low

814809

CUX1
Homeobox protein cut-like 1

1

0

High-throughput

0.232

Low

870233

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.232

Low

1126289

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.232

Low

1126304

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1126325

CTL5
Choline transporter-like protein 5

1

0

High-throughput

0.232

Low

1126339

LRC46
Leucine-rich repeat-containing protein 46

1

0

High-throughput

0.232

Low

1126359

TMM59
Transmembrane protein 59

1

0

High-throughput

0.232

Low

1126374

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025