HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: CBX2 (Q14781)
Chromobox protein homolog 2
Gene: CBX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	37014752, 21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 532
+	Hs
		586751 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00
+	Hs
		123230 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89
+	Hs
		123175 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89
+	Hs
		934567 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63
+	Hs
		587067 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63
+	Hs
		934093 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CBX1_HUMAN (18-153): 1.81e-38: 141: 22.79
+	Hs
		934490 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CBX8_HUMAN (3-238): 1.39e-35: 139: 29.39
+	Hs
		327836 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CBX7_HUMAN (3-210): 1.4e-35: 135: 27.98
+	Hs
		586994 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CBX8_HUMAN (3-238): 1.39e-35: 139: 29.39
+	Dm
		398980 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		HP1_DROME (12-113): 1.11e-26: 109: 30.56