HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 406
+	Hs
		987976 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		952292 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		935154 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		1086286 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		952576 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		828206 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		717680 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		717875 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		717557 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		935031 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RN138_HUMAN (31-190): 6.27e-46: 160: 18.68
+	Hs
		584928 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		935164 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		BARD1_HUMAN (4-335): 2.56e-39: 151: 13.35
+	Hs
		935201 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		952582 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		BARD1_HUMAN (4-335): 2.56e-39: 151: 13.35
+	Hs
		1086305 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		952606 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		935183 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		952593 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		749363 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		749374 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63