HitPredict

Interactor 1: PLXA2 (P70207)
Plexin-A2 (Plex 2) (Plexin-2)
Gene: Plxna2

Interactor 2: PLXA2 (P70207)
Plexin-A2 (Plex 2) (Plexin-2)
Gene: Plxna2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 20877282, 20881961
Identification Methods molecular sieving, light scattering, x-ray crystallography, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Plexin_cytopl~Plexin_cytopl, Plexin_RBD~Plexin_RBD, PSI~Sema, PSI~TIG, PSI~TIG_2, PSI~TIG_plexin, Sema~Sema, Sema~TIG, Sema~TIG_plexin, TIG~TIG, TIG_plexin~TIG_plexin
Common GO terms GO:0001756 - somitogenesis
GO:0002116 - semaphorin receptor complex
GO:0005886 - plasma membrane
GO:0007162 - negative regulation of cell adhesion
GO:0007166 - cell surface receptor signaling pathway
and 12 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1894
Mm

1 1894
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+ Mm
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+ Dm
+ Hs
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024