Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: MBD3 (Q9Z2D8)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18454139
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~MBD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000792 - heterochromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 488
Mm

1 285
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024