HitPredict

Interactor 1: ITA1 (P56199)
Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)
Gene: ITGA1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007229 - integrin-mediated signaling pathway GO:0016020 - membrane GO:0043410 - positive regulation of MAPK cascade and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1179 Hs			1 191
+	Hs
		601224 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Hs
		940358 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17
+	Hs
		940349 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		940350 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		940347 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		580958 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		466176 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		940345 ITA1_HUMAN (1-1179): 0: 1328: 100.00		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		601167 ITA2_HUMAN (22-1178): 0: 1077: 39.17		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Hs
		603772 ITA2_HUMAN (22-1178): 0: 1077: 39.17		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		603774 ITA2_HUMAN (22-1178): 0: 1077: 39.17		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		603766 ITA2_HUMAN (22-1178): 0: 1077: 39.17		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		603764 ITA2_HUMAN (22-1178): 0: 1077: 39.17		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32
+	Hs
		601173 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94
+	Hs
		654958 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31
+	Hs
		654951 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00
+	Hs
		654953 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		580877 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75
+	Hs
		466108 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		654950 ITA6_HUMAN (8-512): 5.11e-60: 227: 16.79		RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32