HitPredict

Interactor 1: S10A1 (P56565)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100a1

Interactor 2: S10A1 (P56565)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100a1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10869553
Identification Methods	mass spectrometry studies of complexes
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EF-hand_1~EF-hand_1, EF-hand_1~S_100, S_100~S_100
Common GO terms	GO:0005509 - calcium ion binding GO:0005739 - mitochondrion GO:0008016 - regulation of heart contraction GO:0016529 - sarcoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 94 Mm			1 94
+	Hs
		1214472 Q5T7Y6_HUMAN (1-94): 2.43e-42: 136: 92.55		Q5T7Y6_HUMAN (1-94): 2.43e-42: 136: 92.55
+	Hs
		657018 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55
+	Hs
		682510 Q5T7Y6_HUMAN (1-94): 2.43e-42: 136: 92.55		S100P_HUMAN (3-90): 1.77e-33: 112: 54.55
+	Hs
		407637 Q5T7Y6_HUMAN (1-94): 2.43e-42: 136: 92.55		S100B_HUMAN (3-90): 2.95e-30: 104: 57.96
+	Hs
		731754 S10AB_HUMAN (2-92): 1.98e-36: 120: 40.66		S10AB_HUMAN (2-92): 1.98e-36: 120: 40.66
+	Hs
		657019 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S100P_HUMAN (3-90): 1.77e-33: 112: 54.55
+	Hs
		657041 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S100Z_HUMAN (1-92): 1.36e-33: 112: 57.61
+	Hs
		657021 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S10A4_HUMAN (1-90): 9.67e-33: 111: 47.78
+	Mm
		450158 S10A1_MOUSE (1-94): 1.48e-37: 123: 100.00		S10A4_MOUSE (1-90): 6.1e-33: 111: 48.89
+	Hs
		657022 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S10A2_HUMAN (1-90): 4.89e-32: 109: 51.11
+	Hs
		657024 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S10A3_HUMAN (1-90): 9.61e-31: 106: 41.11
+	Hs
		407580 S10A1_HUMAN (1-94): 2.59e-38: 124: 92.55		S100B_HUMAN (3-90): 2.95e-30: 104: 57.96
+	Hs
		954940 S10AA_HUMAN (1-91): 7.56e-34: 113: 47.25		S10AA_HUMAN (1-91): 7.56e-34: 113: 47.25
+	Hs
		1204007 HORN_HUMAN (1-88): 3.22e-32: 119: 35.23		FILA2_HUMAN (3-93): 7.93e-28: 106: 37.36
+	Hs
		954979 S10AA_HUMAN (1-91): 7.56e-34: 113: 47.25		S100Z_HUMAN (1-92): 1.36e-33: 112: 57.61
+	Hs
		407589 S10AB_HUMAN (2-92): 1.98e-36: 120: 40.66		S100B_HUMAN (3-90): 2.95e-30: 104: 57.96
+	Mm
		728047 S10A9_MOUSE (2-94): 4.34e-33: 112: 32.98		S10A9_MOUSE (2-94): 4.34e-33: 112: 32.98
+	Hs
		754563 S10AA_HUMAN (1-91): 7.56e-34: 113: 47.25		S10A3_HUMAN (1-90): 9.61e-31: 106: 41.11
+	Hs
		407671 S100Z_HUMAN (1-92): 1.36e-33: 112: 57.61		S100B_HUMAN (3-90): 2.95e-30: 104: 57.96
+	Mm
		690066 S10A9_MOUSE (2-94): 4.34e-33: 112: 32.98		S10A8_MOUSE (1-93): 2.96e-26: 94.1: 30.11