HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: ANK2 (Q01484)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Gene: ANK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29867141, 36950384, 20562859
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015031 - protein transport GO:0051117 - ATPase binding GO:0070972 - protein localization to endoplasmic reticulum
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 3957
+	Hs
		327951 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		ANK2_HUMAN (1-3957): 0: 1794: 100.00
+	Hs
		1030688 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		ANK2_HUMAN (1-3957): 0: 1794: 100.00
+	Hs
		1030682 MLP3C_HUMAN (5-116): 5.11e-45: 144: 42.11		ANK2_HUMAN (1-3957): 0: 1794: 100.00
+	Hs
		1030691 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		ANK2_HUMAN (1-3957): 0: 1794: 100.00
+	Hs
		1030686 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		ANK2_HUMAN (1-3957): 0: 1794: 100.00
+	Hs
		327980 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		ANK3_HUMAN (2-747): 6.95e-177: 619: 33.33
+	Hs
		1091456 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		ANK3_HUMAN (2-747): 6.95e-177: 619: 33.33
+	Hs
		1091452 MLP3C_HUMAN (5-116): 5.11e-45: 144: 42.11		ANK3_HUMAN (2-747): 6.95e-177: 619: 33.33
+	Hs
		1091460 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		ANK3_HUMAN (2-747): 6.95e-177: 619: 33.33
+	Hs
		1091454 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		ANK3_HUMAN (2-747): 6.95e-177: 619: 33.33
+	Hs
		952372 GBRL2_HUMAN (1-117): 1.09e-58: 178: 100.00		ANFY1_HUMAN (368-1078): 5.27e-107: 375: 17.71
+	Hs
		328181 GBRAP_HUMAN (1-117): 7.58e-57: 173: 57.27		ANFY1_HUMAN (368-1078): 5.27e-107: 375: 17.71
+	Hs
		1430354 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		ANFY1_HUMAN (368-1078): 5.27e-107: 375: 17.71
+	Hs
		1417419 MLP3C_HUMAN (5-116): 5.11e-45: 144: 42.11		ANFY1_HUMAN (368-1078): 5.27e-107: 375: 17.71
+	Hs
		1428399 MLP3B_HUMAN (2-117): 6.37e-44: 141: 38.14		ANFY1_HUMAN (368-1078): 5.27e-107: 375: 17.71