HitPredict

Interactor 1: ACTB (P60710)
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: COTL1 (Q9CQI6)
Coactosin-like protein
Gene: COTL1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.680

Property	Details
Experiments	11785969
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 142
+	Hs
		1160646 ACTBL_HUMAN (2-375): 0: 735: 91.71		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Hs
		506950 POTEI_HUMAN (1-375): 0: 731: 91.20		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Hs
		953170 ACTB_HUMAN (1-375): 0: 603: 100.00		DBNL_HUMAN (1-142): 1.29e-53: 176: 23.81
+	Hs
		952811 ACTB_HUMAN (1-375): 0: 603: 100.00		COTL1_HUMAN (1-142): 8.21e-55: 170: 95.07
+	Hs
		993171 ACTG_HUMAN (1-375): 0: 601: 98.93		COTL1_HUMAN (1-142): 8.21e-55: 170: 95.07
+	Mm
		993114 ACTG_MOUSE (1-375): 0: 601: 98.93		COTL1_MOUSE (1-142): 1.13e-54: 169: 100.00
+	Hs
		995882 ACTC_HUMAN (2-375): 0: 592: 94.12		DBNL_HUMAN (1-142): 1.29e-53: 176: 23.81
+	Hs
		996451 ACTS_HUMAN (2-375): 0: 592: 93.58		COTL1_HUMAN (1-142): 8.21e-55: 170: 95.07
+	Ce
		534399 ACT2_CAEEL (2-375): 0: 600: 98.13		Q9XUT0_CAEEL (1-142): 9.83e-45: 156: 21.38
+	Hs
		952855 ACTB_HUMAN (1-375): 0: 603: 100.00		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Hs
		993194 ACTG_HUMAN (1-375): 0: 601: 98.93		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Hs
		995623 ACTC_HUMAN (2-375): 0: 592: 94.12		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Hs
		977706 ACTA_HUMAN (2-375): 0: 591: 94.12		DREB_HUMAN (1-132): 8.45e-44: 153: 18.52
+	Sc
		587330 ACT_YEAST (1-375): 0: 591: 88.80		ABP1_YEAST (1-141): 1.3e-38: 139: 13.89