HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: LBR (Q14739)
Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase)
Gene: LBR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 615
+	Hs
		1131827 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		988371 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		1015443 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		962054 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		581054 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		466255 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		953453 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		601479 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		1433559 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		988789 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		1015877 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		955714 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		962593 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		581353 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		466509 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		953733 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00
+	Hs
		1271031 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		DHCR7_HUMAN (203-615): 5.81e-169: 491: 34.00